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mesenchymal stem cells adipogenic differentiation medium  (Procell Inc)

 
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    Procell Inc mesenchymal stem cells adipogenic differentiation medium
    Mesenchymal Stem Cells Adipogenic Differentiation Medium, supplied by Procell Inc, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mesenchymal+stem+cells+adipogenic+differentiation+medium/pmc12822967-71-2-16?v=Procell+Inc
    Average 86 stars, based on 1 article reviews
    mesenchymal stem cells adipogenic differentiation medium - by Bioz Stars, 2026-07
    86/100 stars

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    Schematic conceptualization of this study. IR activated the NF-κB signaling pathway to promote activation and maturation of DCs, amplifying inflammatory signals through the release of pro-inflammatory cytokines. The mDCs triggered oxidative stress of BMSCs, showing increased intracellular ROS levels, inhibited osteogenic differentiation, and enhanced adipogenic differentiation, which accelerated the progression of radiation-induced jaw injury. VitD3-induced tolDCs exhibited IR resistance and anti-inflammatory properties, possessing the therapeutic potential to accelerate bone regeneration in irradiated jaw defects through local administration. (IR: ionizing radiation; mDC: mature dendritic cell; tolDC: tolerogenic dendritic cell; BMSC: bone marrow mesenchymal stem cell; ROS: reactive oxygen species; vitamin D3: vitD3)

    Journal: Stem Cell Research & Therapy

    Article Title: Ionizing radiation-mediated dendritic cell maturation exacerbates inflammatory response of bone marrow mesenchymal stem cells and impairs osteogenesis in radiation-induced jaw injury

    doi: 10.1186/s13287-025-04508-x

    Figure Lengend Snippet: Schematic conceptualization of this study. IR activated the NF-κB signaling pathway to promote activation and maturation of DCs, amplifying inflammatory signals through the release of pro-inflammatory cytokines. The mDCs triggered oxidative stress of BMSCs, showing increased intracellular ROS levels, inhibited osteogenic differentiation, and enhanced adipogenic differentiation, which accelerated the progression of radiation-induced jaw injury. VitD3-induced tolDCs exhibited IR resistance and anti-inflammatory properties, possessing the therapeutic potential to accelerate bone regeneration in irradiated jaw defects through local administration. (IR: ionizing radiation; mDC: mature dendritic cell; tolDC: tolerogenic dendritic cell; BMSC: bone marrow mesenchymal stem cell; ROS: reactive oxygen species; vitamin D3: vitD3)

    Article Snippet: BMSCs were co-cultured with DC-CM and OriCell SD rat bone marrow mesenchymal stem cell adipogenic differentiation basal medium (Cyagen, USA) for 7 days.

    Techniques: Activation Assay, Irradiation